Fibroma of tendon sheath is a benign tumor that presents as a small subcutaneous nodule that slowly increases in size.
The tumors often have a multinodular growth pattern, with individual nodules being composed of bland, slender, spindle-shaped cells (myofibroblasts) in a dense, fibrous matrix.”
A common microscopic finding is the presence of elongated, slit-like blood vessels.
The lesions nearly always arise in the distal portions of the extremities.
They often occur on the fingers, hands, toes, or feet. Although they are benign, they may recur in up to 40% of cases.
Although they may be regarded as a tumor of the skin, the lesions arise from tendons and aponeuroses in superficial sites, and are therefore properly classified as in the category "soft tissue tumor."
The World Health Organization, 2020, reclassified these tumors as a specific, benign tumor type in a broad category of soft tissue
neoplasms
A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
termed
fibroblastic and myofibroblastic tumors
Fibroblastic and myofibroblastic tumors (FMTs) develop from the mesenchymal stem cells which differentiate into fibroblasts (the most common cell type in connective tissue) and/or the myocytes/ myoblasts that differentiate into muscle cells. ...
.
The biological nature of Fibroma of tendon sheath is not known, but the category appears to comprise a number of different pathologic processes.
It is considered that about one-third of the lesions in this category may be acral variants of the entity, nodular fasciitis.
See also
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Giant cell tumor of the tendon sheath
Tenosynovial giant cell tumor (TGCT) is a group of rare, typically non-malignant tumors of the joints. TGCT tumors often develop from the lining of joints (also known as synovial tissue).
Common symptoms of TGCT include swelling, pain, stiffne ...
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List of cutaneous conditions
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. The major function of this system is as a barrier agai ...
References
Dermal and subcutaneous growths
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